Cherry Tree High I! My! Girls! is the sequel to the popular slice-of-life adventure game Cherry Tree High Comedy Club by developer 773.Mairu and friends have successfully re-opened the Cherry Tree High Comedy Club, but now they actually need to act like a club! Mairu’s nemesis Chitose hasn’t run out of tricks to catch them out just yet, so they’ll need to be careful! But Chitose isn’t the only problem that Mairu and friends have to deal with… A rival club is competing for the spot of number one entertainment, and a new transfer student will deeply affect the Comedy Club line-up!